My name is Michael F. Holick Ph.D., M.D. I am currently the Professor of Medicine, Physiology and Biophysics, emeritus chief of the section of Endocrinology, Diabetes and Nutrition, former Director of the Bone Health Clinic, Director of Ehlers Danlos Clinical Research Program and Director of the Vitamin D, Skin and Bone Research Laboratory at Boston University Medical Center. I received both my Ph.D. in Biochemistry and my M.D. degree from the University of Wisconsin.
During my almost 40 years working as a clinician, I treated over 25,000 patients with metabolic bone disease in my practice focusing on calcium, vitamin D, bone metabolism and genetic disorders of collagen-elastin including Osteogenesis Imperfecta, Marfan’s syndrome and Ehlers-Danlos syndrome. I have clinically seen or have followed as part of my clinical research more than 3,000 infants, children and adults with various forms of Ehlers-Danlos syndrome.
I have served in various capacities, including being the chair for NASA’s Research Committee on Human Health and Performance for the bone health of astronauts over the past 35 years. I served on and/or continue to serve on several editorial boards including the American Journal for Bone and Mineral Research, Journal of Clinical Endocrinology and Metabolism, Nutrients, Scientific Reports, Osteoporosis International and the journal Bone. I served as an associate editor for the journal Dermato-Endocrinology and I am editor-in-chief for the Journal of Clinical Laboratory. I have been conducting basic, clinical and translational research in the fields of vitamin D and bone and collagen metabolism for more than 40 years. When I started my career as an endocrinologist at the Massachusetts General Hospital, a Harvard teaching hospital, in my practice I routinely saw infants, children and adults with a wide variety of metabolic bone diseases. I am nationally and internationally recognized for my expertise in pediatric and adult metabolic bone disease including the genetics of metabolic bone disease in infants, children and adults. I have been invited as the Grand Round speaker and keynote speaker for Universities, hospitals and Society meetings. These include, among others, Children’s Mercy Hospitals and Clinics Kansas City Missouri, Children’s Hospital Cincinnati, Children’s Hospital of Philadelphia and Hospital for Sick Children in Toronto. I was a featured speaker or keynote speaker for Academy of Breast-Feeding Medicine in Williamsburg, Virginia, Beverly Hospital’s Annual Pediatric Dinner, Northern New Jersey Pediatric Society, 27th Annual Pediatric Update Conference Danbury Hospital, Department of Pediatrics at Brown University, Barbara Bush Children’s Hospital at Maine Medical Center and American Academy of Pediatrics, Ehlers-Danlos Doctors Speaker Series and most recently featured Speaker for the Chilean Obstetrics/Gynecology Society and keynote speaker for the Italian Society For Osteoporosis and Bone Metabolism just to name a few.
I was invited as the outside expert for a Clinical Pathology Conference for the Harvard Medical School and New England Journal of Medicine about a child presenting with seizures who had severe vitamin D deficiency rickets. I also edited a book on bone health in children entitled Perinatal Calcium and Phosphorus Metabolism and served on the editorial board for the Journal of Pediatrics. I have done and continue to do both basic and clinical genetics research and was the author for the chapter Genetics of Vitamin D Disorders for the textbook Genetic Diagnosis of Endocrine Disorders. I wrote the review on Vitamin D Deficiency for the New England Journal of Medicine1 and alerted health care professionals worldwide about the unrecognized vitamin D deficiency and rickets epidemic in the review Resurrection of Vitamin D Deficiency Rickets in the Journal of Clinical Investigation 2006.2
I have published over 600 manuscripts in well-respected peer-reviewed journals and more than 200 reviews and book chapters. There have been more than 150,000 citations for my work in the field of calcium, vitamin D and bone metabolism on Google scholar. I served as the Chair for the Endocrine Society’s Clinical Practice Guidelines Committee for Vitamin D that published recommendations for how to treat and prevent vitamin D deficiency in children and adults.3 I have been considered by Castle Connolly as one of America’s Top Doctors for the past 19 years. Thompson Reuters in 2014 considered me to be one of the World’s Most Influential Scientific Minds, Clinical Medicine. In 2019 I was elected as a Fellow in the American Society for Clinical Nutrition and was elected into the Orthomolecular Medicine Hall of Fame. In 2019, the journal Current Opinion in Pediatrics invited be to write an up-to-date review on bone fragility for pediatricians. The review, Diagnosis and management of pediatric metabolic bone diseases associated with skeletal fragility was published in Current Opinion in Pediatrics 32;560-573: August 2020.4
1 Holick, M.F. Vitamin D Deficiency. New Engl. J. Med. 2007. 357:266-81
2 Holick, M.F. Resurrection of Vitamin D deficiency and rickets. J Clin Invest. 2006. 116(8):2062-2072
3 Holick, MF, Binkley, NC, Bischoff-Ferrari, HA, et al. (2011). Evaluation, treatment, and prevention of Vitamin D deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 96:1911-30.
4 Charoenngam, N, Cevik, MB, Holick, MF Diagnosis and management of pediatric metabolic bone diseases associated with skeletal fragility, Current Opinion in Pediatrics. 2020;32(4).